In principle, try to avoid the use of antihistamine drugs during pregnancy.When the antihistamine is used to be treated, the patient should be informed that there are currently no absolutely safe and reliable drugs.Now, according to the clinical diagnosis and treatment guidelines, pharmaceutical manuals, and the US FDA pregnancy grading, several drugs with higher safety of anti -allergic drugs are summarized as follows.
1. deedstone
1. Indications:
It is used to alleviate the symptoms of allergic rhinitis, and it is also suitable for alleviating symptoms and signs of chronic urticaria, itching skin diseases and other allergic skin diseases.
2. Recommended basis:
2014 version of "Chinese urticaria diagnosis and treatment guidelines": Choose relatively safe and reliable drugs such as decentralized and reliable drugs such as depleted and disadvantaged;
US Food and Drug Administration (FDA) pregnancy safety grading: Class B;
Domestic drug instructions: The safety of women during pregnancy has not been determined, and it should be used with caution.
Reminder: Clothery is definitely the second -generation antihistamine drug at present. The report from the Swedish Medical Registration Department pointed out that the incidence of urinary cracks in the middle urethral cracks of about 3,000 pregnant women during pregnancy is ordinary.Two times the person, but the report is limited.
3. Use medication:
Oral administration, 10mg at a time, once a day.Do not increase the dose without authorization. Excessive use can cause drowsiness, tachycardia and headache.
Antimamines can remove or reduce the skin’s positive response to all changes to the original, so it should be stopped using deretthe about 48 hours before the skin test.
Second, Cidalizine
1. Indications:
For seasonal or perennial allergic rhinitis, urticaria and skin itching of the skin caused by allergens.
2. Recommended basis:
US Food and Drug Administration (FDA) pregnancy safety grading: Class B;
Domestic drug instructions: Although animal teratogenic test shows that there is no teratogenic effect, it is still not recommended for women during pregnancy.
Reminder: There are currently no clinical research materials for pregnant women who are not sufficient and strictly controlled.Because animal reproductive research does not always predict the impact of drugs on people, it can only take this product during pregnancy only when it is really needed and knows the consent.
3. Use medication:
Oral administration, 10 mg at a time, once a day.You can use a small amount of liquid at dinner. If you are sensitive to adverse reactions, you can once every morning and evening, 5 mg once a day.
Food can delay the blood drug concentration of this drug 1.7 hours, and the blood drug concentration is reduced by 23%.
Hydroxylzine is a precursor drug of Setrizine, which is disabled to patients with allergic hydroxyzine allergic and severe renal damage.
It is not advisable to drive during the medication.
Avoid taking this medicine within 24 hours before specific skin tests, specific degeneration tests or airway reactivity tests.
Those who take the medication for more than one month should change the medicine appropriately to prevent drug resistance to this medicine.
Third, chlorophenicamin
1. Indications:
Suitable for skin allergies: urticaria, eczema, dermatitis, medicinal rash, skin itching, neurodermatitis, worm bites, solar dermatitis.It can also be used for allergic rhinitis, blood vessels, phytitis rhinitis, drugs and food allergies.
2. Recommended basis:
American Food and Drug Administration (FDA) pregnancy safety grading: C -level;
Domestic drug instructions: Pregnant women use it with caution.
3. Use medication:
Oral administration, 4mg at a time, 3 times a day.
During the medication, you must not drive the aircraft, cars, boats, and operation of precision instruments.
This product has anti -M choline receptor effects, bladder cervical obstruction, pyloric duodenal intestinal obstruction, glaucoma, digestive ulcers, use it with caution.
This product cannot be applied to patients with lower respiratory tract infections and asthma attacks (the disease can be aggravated due to the thickest sputum).
Fourth, benzene, Liming
1. Indications:
It is used for skin allergies such as urticaria, eczema, dermatitis, rash, itching, neurodermatitis, worm bites, sunci dermatitis, allergic rhinitis and food, drug allergies.
2. Recommended basis:
National Food and Drug Administration (FDA) pregnancy safety grading: Grade B;
Domestic drug instructions: Pregnant women are disabled.
Reminder: This medicine can be used through the placenta and this medicine during pregnancy. The incidence of infant cleft palate, groin hernia, and urogenital organs may increase, so women in pregnancy should be used with caution.
3. Use medication:
Orally, 25 mg once a day, 2-3 times a day.
This product has anti -M choline receptor effects, bladder cervical obstruction, pyloric duodenal intestinal obstruction, glaucoma, digestive ulcers, use it with caution.
During the medication, you must not drive the aircraft, cars, boats, and operation of precision instruments.
Oral administration is used for preventing and faint diseases, and this product should be used 1 to 2 hours before travel.
Five, Saidhine
1. Indications:
For allergic diseases, such as urticaria, pimples, urticaria, eczema, and itching of the skin.
2. Recommended basis:
National Food and Drug Administration (FDA) pregnancy safety grading: Grade B;
Domestic drug instructions: Pregnant women are disabled or used with caution.
3. Use medication:
Oral, 2-4 mg at a time, 2-3 times a day.
Those with viscosity of sputum should not use this medicine.
During the medication, you must not drive the aircraft, cars, boats, and operation of precision instruments.
During the medication, it should be avoided under the sun or sunlight for a long time.
Six, Meng Lu Ste sodium
1. Indications:
For the prevention and long -term treatment of asthma, reduce the symptoms caused by seasonal allergic rhinitis.
2. Recommended basis:
National Food and Drug Administration (FDA) pregnancy safety grading: Grade B;
Domestic drug instructions: Research materials without pregnancy without pregnancy, unless they are clearly needed, pregnant women should avoid taking this product.
Reminder: No study of pregnant women has been conducted, but in animal reproductive research, no impact on the fetus has been seen.Experience after the global listing shows that there are rare newborns after the use of this product during pregnancy.Most of these women also use other asthma treatment drugs during pregnancy.The use of this product has not yet established the cause and effect of these events.
3. Use medication:
Oral administration, once a day, 10mg each time.
Asthma patients should take it before going to bed.Patients with allergic rhinitis can take the medicine when they need them according to their own situation.At the same time, patients with asthma and seasonal allergic rhinitis should be taken once a night.
The efficacy of orally for the treatment of acute asthma seizures has not been determined.Therefore, it is not used in the treatment of acute asthma.
7. Buddine powder inhalation agent
1. Indications:
For patients with bronchial asthma and asthma -dependent bronchial asthma and asthma chronic bronchitis for non -glucocortic hormone -dependent or glucocorticoids.
2. Recommended basis:
National Food and Drug Administration (FDA) pregnancy safety grading: C -level;
Domestic pharmaceutical description: A large number of forward -looking epidemiological research results and world -wide market experience did not find that the use of inhaled Bu Di Neid during pregnancy will have a bad role in embryo and newborn.
3. Use medication:
Spray inhalation: 200-1600 μg a day, divided into 2-4 times.Generally one time at a time, once in the morning and evening, a total of 400 μg a day; when the condition is severe, 200 μg once, 4 times a day, a total of 800 μg a day.
Should not try to inhale the acute attack of asthma by inhaling the inhalation of Bu Di, at this time, the short -acting bronchial extension is still needed.
Mild throat stimulation, cough, hissing, ornamental pearl infection.In order to minimize the incidence of fungal oralitis, patients should be instructed to rinse with water with water after each suction.
Kind tips:
The first -generation antihistamine drugs lacked a clinical control study of large samples, and benzenerara and Cyacinhaide were banned by domestic drug descriptions. Unless clinical essentials were necessary, they should be avoided when they were not known to patients.
There are many major samples of children and pregnant women in the second -generation antihistamine drugs. The long -term observation time and the data are detailed. Clinicians can choose chlorine in priority according to the actual situation.
